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標靶治療 Targeted Therapy

認識標靶治療

認識標靶治療

標靶治療(Targeted therapy)從技術層面而言,也被視為化療的一種,因兩者皆用藥物擊殺癌細胞。
不過,因為標靶治療的原理與傳統化療大不同,故可以做到清除癌細胞之餘,不影響其他普通細胞。1,2

標靶治療是甚麼?

標靶治療的原理

標靶治療所用的藥物,會攻擊癌細胞上特定的範圍或物質,例如細胞內非正常的基因變化、一般細胞不會出現或已變異的蛋白等。2
而標靶藥物發揮作用的主要方式如下:2

阻止癌細胞接收刺激生長及進行細胞分裂的化學信號

改變癌細胞內的蛋白質,令癌細胞死亡

阻止腫瘤生長新血管,令癌細胞得不到養分

激發身體的免疫系統自行殺死癌細胞

將毒素輸送到癌細胞,將其殺死

標靶治療的種類

標靶治療藥物有大小之分,體積令運作方式不同。小分子藥物(Small molecule drug)能進入癌細胞內,再以阻擾細胞內某種特定物質為目標;大分子藥物(Large molecule drug)則一般不能進入癌細胞內,遂主要用作削弱或破壞癌細胞表面的蛋白質或酶(enzyme)。2

甚麼人適合標靶治療?

病人支援

確診癌症後,有甚麼可以問醫生?

以下是一些可能幫助癌症患者了解自己是否需要標靶治療,並與醫生討論治療方案的相關問題:4,5

  • 我需要接受標靶治療嗎?接受標靶治療期間要住院嗎?
  • 標靶藥要吃多久?
  • 標靶治療是化療嗎?
  • 標靶治療的成功率有多大?完成療程後還可以生存多久?
  • 吃標靶藥期間,在飲食上有限制嗎?
  • 標靶治療會導致甚麼副作用?如出現副作用,可以怎麼處理?
  • 除了標靶治療,我還需要接受其他治療(如手術、放射治療)嗎?

立即向醫生發問,現在問,發現更多可能!

  1. Drug Office, Department of Health, HKSAR. 標靶治療藥. Available at: drugoffice.gov.hk/eps/do/tc/consumer/news_informations/dm_33.html. Accessed Aug 2024.
  2. American Cancer Society. How targeted therapies are used to treat cancer. Available at: www.cancer.org/cancer/managing-cancer/treatment-types/targeted-therapy/what-is.html. Accessed Aug 2024.
  3. American Cancer Society. Targeted therapy side effects. Available at: www.cancer.org/cancer/managing-cancer/treatment-types/targeted-therapy/side-effects.html. Accessed Aug 2024.
  4. Cancer Council. Question checklist for targeted therapy. Available at: www.cancercouncil.com.au/wp-content/uploads/2021/07/Question-checklist_Targeted-therapy.pdf. Accessed Aug 2024.
  5. MedlinePlus. Targeted therapy: Questions to ask your doctor. Available at: medlineplus.gov/ency/patientinstructions/000829.htm. Accessed Aug 2024.

此網站為香港市民而設。內容僅供參考,並不能代替醫生的診斷或建議。詳情請向醫生查詢。

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} .p2_table table tbody tr,.p2_table table tbody tr:nth-child(even),.p2_table_2 table tbody tr,.p2_table_2 table tbody tr:nth-child(even){ background-color:#FFF3FB; } .p2_table table thead th:nth-child(1){ background-color:#FFF3FB; border-radius: 25px 25px 0 0; padding-top: 10px; } .p2_table_2 table thead th:nth-child(1){ background-color:#FFF3FB; border-radius: 10px 10px 0 0; padding:5px 0px; } .p2_table_2 table thead th:nth-child(2){ width:0px; } .p2_table table thead th:nth-child(2),.p2_table table thead th:nth-child(3){ background-color:#F2F2F3; border-radius: 25px 25px 0 0; padding-top: 10px; } .p2_table table tbody td:nth-child(2),.p2_table table tbody td:nth-child(3){ color:#000; font-weight: 700; } .p2_table table tbody td:nth-child(2) ul{ margin:0px; display: inline-block; width: 190px; } .p2_table table tbody td:nth-child(3) ul{ margin:0px; display: inline-block; width: 280px; } .p2_table ,.p2_table_2{ color:#331C3A; font-weight: 700; } .p2_table table tbody tr:nth-child(4) td:nth-child(1){ border-radius: 0px 0px 0px 25px; } .p2_table table tbody tr:nth-child(4) td:nth-child(3){ border-radius: 0px 0px 25px 0px; } .p2_sub_col1 div.mh-columns-inner div.mh-column,.p2_sub_col2 div.mh-columns-inner div.mh-column{ margin:0px; } .p4_list{ max-width:600px; } .plan_btn1{ width: 225px; } .QA_img{ min-width:65px; width:65px; } .QA_bar{ width:100%; max-width:800px; } .support_btn1{ width: 255px; } .QA_btn1{ width:250px; } figure.lightning{ width:200px; margin:auto; } ul.p4_tab_list_1 li::before{ background-color:#331C3A; } ul.p4_tab_list_1 li{ margin: 0; } ul.p4_tab_list_1 { margin: 0px; padding: 0px; } #what_is .pie_chart_text2{ width:100%; text-align:right; } figure.img_pie_chart_line1 { width: 30%; margin-top: -16%; margin-left: 50%; margin-bottom: -3%; } figure.img_pie_chart_line2 { width: 10%; margin-top: -4%; margin-left: 35%; margin-bottom: -10%; z-index: 1; } .p2_dot_list{ gap: 0em; } .p4_stack .p2_dot_list{ width:100%; } .p4_stack .p2_dot_list p{ text-align:justify; margin-top: -5px; } #what_is .p2_dot_list p { text-align:left; margin-top: -5px; } .p2_dot{ width:18px; height:18px; min-width:18px; min-height:18px; } .w100{ width:100%; } #mconnect-theme-banner-container-4373 > div > div > div > div > div.banner__content.sub__entry__content > div > a,#mh_back_to_top_link > a,.cta_btn { background-color:#4e3668; border: 1px #FFF solid; } sup{ white-space: pre; } .mh-nav-side-accordion ul li{ margin: 20px 0; } .mh-tabs–primary .mh-tabs-nav .mh-tabs-control .mh-tabs-control-next, .mh-tabs–primary .mh-tabs-nav .mh-tabs-control .mh-tabs-control-prev{ padding: 0px 8px; height: 40px; } .QA_list{ max-width: 800px; width: 100%; } .mh-nav–primary li:hover{ color: #298C89; border-bottom: 0.125rem solid; padding: 0 0; height: 40px; } .mh-nav–primary .mh-submenu li:hover{ color: #298C89; border: none; padding: 0 0; height: 40px; } .footer_code::before { content: “HK-KEY-00977 May/2025”; color:#000; }