乳癌 Breast Cancer
認識乳癌
乳癌是一種在乳房組織內形成的癌症,
絕大部份患者均為女性,
但極小數男性也可能患上乳癌。1
乳癌是甚麼?
乳癌種類
乳癌是發生在乳房組織的癌症,大約70%-75%個案均於乳腺管中形成(在乳房負責將乳汁引導至乳頭的組織),另有約10%-15%則源自乳小葉。2, 3
乳癌常見類型為:
-
入侵性乳腺管癌(Invasive Ductal Carcinoma(IDC))
-
最常見的乳癌,約佔乳癌的70%-75%
-
原發於乳腺管,並穿透管壁入侵乳房脂肪組織
-
入侵性乳小葉癌(Invasive Lobular Carcinoma(ILC))
其他類型的乳癌包括炎性乳癌、柏哲氏病等,但這些就較為少見。
除了病理分類,乳腺癌一般可按照雌體素受體(ER)、黃體酮受體(PR)、第二型人類上皮生長素受體(HER2)的型態,及癌症生長指數(Ki-67),大概分為四個主要生物學亞型4-7:
亞型 | 生物標記表現 | 特性 |
---|
管腔A型 |
- ER陽性及PR陽性
- HER2陰性
- Ki-67 較低水平(<14%)
|
- 生長速度相對其他亞型慢,惡性較低,對治療反應較佳
- 佔所有乳癌個案約50%
|
管腔B型 |
- ER陽性/或PR陽性
- HER2陰性
- Ki-67 較高水平
或
- ER陽性或PR陽性
- HER2陽性
- Ki-67 任何水平
|
- 生長速度較快,體積較大,惡性較高,更具侵略性,容易復發
- 佔所有乳癌個案約15%-20%
|
HER2陽性 |
|
- 生長速度快,侵略性較大,惡性較高(擴散速度可能較快8),通常較遲發現
- 佔所有乳癌個案約10%
|
三陰性 |
|
- 生長速度快,侵略性大,惡性高
- 與其他亞型相比,擴散速度在幾個類別中最快8
- 佔所有乳癌個案約20%
|
-
ER陽性及PR陽性
-
HER2陰性
-
Ki-67 較低水平(<14%)
-
生長速度相對其他亞型慢,惡性較低,對治療反應較佳
-
佔所有乳癌個案約50%
-
ER陽性或PR陽性
-
HER2陰性
-
Ki-67 較高水平
或
-
ER陽性或PR陽性
-
HER2陽性
-
Ki-67 任何水平
-
生長速度較快,體積較大,惡性較高,更具侵略性,容易復發
-
佔所有乳癌個案約15%-20%
- 生長速度快,侵略性較大,惡性較高(擴散速度可能較快8),通常較遲發現
- 佔所有乳癌個案約10%
-
生長速度快,侵略性大,惡性高
-
與其他亞型相比,擴散速度在幾個類別中最快8
-
佔所有乳癌個案約20%
乳癌統計數字
在香港,乳癌是女性最常見的癌症,2022年共5,182宗新症,並有792人因乳癌死亡。4 以一生累積風險計算,大約每14名女性便有一人最終會患上乳癌。4 此外,本港數據亦顯示,乳癌發病率近年有持續上升的趨勢,每年確診個案由2001年1,997宗倍升至2022年的5,182宗。9
乳癌的成因
乳癌的成因與很多因素有關,包括2,10:
-
女性
-
年齡:年紀愈大,患癌機會愈高
-
家族病史
-
遺傳基因:約5-10%乳癌屬遺傳性個案
-
曾接受放射治療
-
肥胖
-
未曾或遲生育
-
未曾喂哺母乳
-
早來月經
-
接受荷爾蒙補充療法
-
吸煙
-
缺乏運動
根據本地近2萬名乳癌患者的資料分析,四大最常見的風險因素為3:
77.5%
缺乏運動
(每周少於3小時的運動)
65.9%
未有餵哺母乳
38.7%
超重/肥胖
37.0%
感到很大壓力
乳癌症狀
每位乳癌患者的情況都不同,因此症狀也未必一樣,部分人更可能毫無徵狀。11
乳癌常見症狀有11-13:
任何人如出現上述症狀和前兆或懷疑自己患上乳癌,都應盡早求醫,進行相關檢查,確定病因。
乳癌分期
目前乳癌的分期主要依據TNM系統為骨幹,按照腫瘤大小和影響範圍(T)、腋下淋巴結轉移情況(N),以及是否擴散至其他器官(M)等歸類為第一至四期。第一及二期屬於早期癌症,第三及四期則為較晚期。14,15
分期 | | | |
---|
乳癌0期16,17又稱原位癌 |
- 原位乳癌,屬最早期的乳癌
- 癌細胞局限在乳腺管內,未有侵入乳腺管以外組織
|
|
腫瘤大小
|
擴散情況
|
第1期18,19
|
A
|
≤2厘米
|
未擴散到乳房以外
|
B
| 未發現≤2厘米 |
擴散到乳房附近淋巴結
|
第2期20,21
|
A
| 未發現≤2厘米 |
擴散到1-3顆腋下淋巴結
|
>2至≤5厘米 |
沒有擴散
|
B
|
>2至≤5厘米
|
擴散到1-3顆附近淋巴結
|
>5厘米
|
沒有擴散
|
第3期22,23
|
A
| 未見或任何大小 |
擴散到4-9顆附近淋巴結
|
>5厘米
|
擴散到1-3顆附近淋巴結
|
B
|
任何大小
|
擴散到胸壁組織、 乳房皮膚有腫漲、發炎或潰瘍跡象、 可能擴散到高達9顆附近淋巴結
|
C
| 可能未見或任何大小 |
擴散到達10顆或更多腋淋巴結、 胸骨淋巴結和/ 或鎖骨下淋巴結
|
第4期24,25 | |
任何大小
|
擴散到其他器官, 例如骨骼、肺部、肝臟及腦
|
-
原位乳癌,屬最早期的乳癌
-
癌細胞局限在乳腺管內,未有侵入乳腺管以外組織
-
未發現或腫瘤大小≤2厘米
-
擴散情況到乳房附近淋巴結
-
未發現或腫瘤大小≤2厘米
-
擴散情況到1-3顆腋下淋巴結
或
- 腫瘤大小>2至≤5厘米
- 擴散情況到1-3顆附近淋巴結
或
-
任何腫瘤大小
-
擴散到胸壁組織、乳房皮膚有腫漲、發炎或潰瘍跡象、可能擴散到高達9顆附近淋巴結
-
可能未見或任何腫瘤大小
-
擴散到達10顆或更多腋淋巴結、胸骨淋巴結和/或鎖骨下淋巴結
- 任何大小腫瘤
- 擴散情況到其他器官,例如骨骼、肺部、肝臟及腦
診斷及生物標記檢測
當醫生懷疑患者可能患上乳癌,了解病歷後會安排身體及乳房等檢查,如26-29:
-
乳房X光造影檢查(Mammogram)
-
超聲波掃描(Ultrasound scan)
-
超聲波掃描
(Ultrasound scan)
-
活組織檢驗
-
血液檢驗
如果確認患上乳癌後,患者可能需要接受進一步檢驗,確定腫瘤有否擴散,以制訂合適的治療方案,包括:
-
胸部X光
-
電腦掃描
-
骨骼掃描
-
磁力共振
-
正電子掃描
按需要,醫生也可能會建議進行其他檢查以確定病情。
確認乳癌的生物標記特徵有助醫生制訂合適的治療方案,因為每名患者的乳癌特徵都不一樣,生物標記檢測可以幫助了解腫瘤的特性,從而選擇更針對性的治療方案。
乳癌常用生物標記檢測30,31:
-
PD-L1蛋白水平
-
荷爾蒙受體(HR)表現,包括:雌體素受體(ER)、黃體酮受體(PR)
-
第二型人類上皮生長素受體(HER2)表現
-
其他:BRCA1/2基因突變、微衞星不穩定性及錯配修復基因缺陷、突變負荷等
乳癌常用治療
乳癌的治療因人而異,實際治療方案視乎患者的健康狀況、癌症期數及特徵,以及個人意願等等。
以下六類是主要的治療方法32,33:
乳癌治療並不簡單,需要按照分期及亞型(如三陰性、HER2陽性等)而採取適當的治療方案,而一個涵蓋不同專科的跨專業團隊,包括外科、腫瘤科及放射治療科等,通過全面評估患者的身體狀況、個人意願及病情,制訂針對性的個人化治療計劃。40-42
現在問 ,發現更多可能!向醫生了解不同療法的優點和可能副作用,一起制定最適合的治療方案。
常見問題
術前治療(Neo-adjuvant therapy)是在主要療法前(通常為手術或放射治療)的治療方法,旨在於手術/放射治療前將腫瘤縮小。而術後治療(Adjuvant therapy)則指在主要療法後的治療方法,旨在消滅殘餘在體內的癌細胞,從而減低復發風險。43,44
醫學界鼓勵婦女進行定期乳房檢查,包括自我檢查、醫生觸診檢查及乳房X光造影檢查,以及早發現乳癌。45,46 研究顯示,以乳房X光造影檢查的乳癌篩查,可以降低確診時的乳癌期數,從而改善治療方案並提高存活率,將乳癌死亡風險減低約20%。47,48
本地專家組建議,乳癌高風險女性可由35歲或按醫生指示每年接受乳房X光造影檢查,而其他一般風險女性則可根據醫生建議每隔兩年檢查一次。49
曾經或現在患有乳腺癌,並且正在考慮懷孕及生育的患者,請諮詢主診醫生意見。詢問癌症及其治療是否影響胎兒健康,以及完成治療及康復多久才適合計劃孕育新生命。50,51
對於想懷孕但擔心治療後無法受孕的乳癌患者,可以考慮生育科技協助,包括雪藏卵子及人工受孕等。52
如有任何疑慮,患者應諮詢主診醫生的意見。
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padding:0px 0px;
}
.p2_sub_col1 div.mh-columns-inner div.mh-column,.p2_sub_col2 div.mh-columns-inner div.mh-column{
border-bottom:1px solid white;
padding-right: 0;
padding-left: 10px;
}
ul.p2_tabs_list >li{
margin-right: 2px;
margin-bottom: 2px;
}
.p2_sub_col1 div.mh-columns-inner div.mh-column{
width:100%;
margin:0px;
}
ul.mh-footer-menu li:nth-child(n + 6):nth-child(-n + 6){
float: left;
margin: 10px;
}
ul.mh-footer-menu li:nth-child(-n+5){
margin-bottom: 5px;
}
ul.mh-footer-menu li:nth-child(7){
float: right;
}
div.wp-block-group ul.p3_list > li,div.wp-block-group ul.p3_list_1_2 > li,ul.p2_list > li,div.wp-block-group ul.p3_list_2 > li{
margin-right: 0px;
}
.p5_img{
display:none;
}
.p5_img_mob{
display:block;
transform: translate(0px, 70px);
}
.p5_img_mob2 {
padding-top: 30px;
margin-bottom: -65px;
}
}
@media all and (min-width: 768px){
ul.p3_list li:nth-child(3){
display:none;
}ul.p3_list li:nth-child(2){
display:list-item;
}
ul.p3_list_1_2 > li,ul.p3_list > li,ul.p4_list > li{
text-align: center;
}
ul.p3_list strong,ul.p3_list_1_2 strong{
min-width: 80px;
margin: 0;
text-align: left;
display: inline-block;
}
ul.p2_tabs_list >li{
margin-right: 10px;
}
.p2_sub_col1 div.mh-columns-inner div.mh-column div,.p2_sub_col2 div.mh-columns-inner div.mh-column div{
padding-left: 25px;
padding-top: 10px;
padding-bottom: 10px;
}
.p2_sub_col1 div.mh-columns-inner div.mh-column:nth-child(2){
border-left:1px solid white;
border-bottom:1px solid white;
}
.p2_sub_col1 div.mh-columns-inner div.mh-column:nth-child(3){
border-top:1px solid white;
border-right:1px solid white;
}
.p2_sub_col1 div.mh-columns-inner div.mh-column{
width:50%;
margin:0px;
}
ul.p3_list > li,ul.p3_list_1_2 > li, ul.p2_list > li, ul.p4_list > li{
margin-right: 20px;
}
.p5_img{
max-width:300px;
transform: translate(0px, 80px);
z-index:1px;
}
.p5_img_mob{
display:none;
}
}
@media all and (max-width: 575px){
.p4_tabs_tab{
padding-bottom:30px;
}
.p2_sub_col1 div.mh-columns-inner div.mh-column{
width:100%;
}
ul.mh-footer-menu li:nth-child(n + 6):nth-child(-n + 6){
float: left;
margin: 10px;
}
ul.mh-footer-menu li:nth-child(7){
float: right;
}
.col3_2 .mh-columns-inner .mh-column:nth-child(even){
margin-left: 10px;
margin-right: auto;
}.col3_2 .mh-columns-inner .mh-column:nth-child(odd){
margin-left: auto;
margin-right: 10px;
}
.story_col{
width: 100%;
}
.col3_2 div > figure > a > img{
max-width:100px;
}
.col3_2{
padding: 0 15px;
}
.tabs_tab .mh-tabs-nav, .p4_tabs_tab .mh-tabs-nav,.tabs_tab_hide_pc .mh-tabs-nav{
display: block;
}
.tabs_tab .mh-tabs-nav ul li{
max-width: 105px;
}
.hide_pc,.tabs_tab_hide_pc{
display:block;
}
div.show_pc_flex{
display:none;
}
.show_pc{
display:none;
}
.p3_tabs_tab,.p5_stack{
padding:0 30px;
}
.col_block{
min-height:150px;
}
}
#mh_content{
margin:0px;
background: #FFFFFF
}
.p2line{
width:100%;
}
.title_line{
width:100%;
max-width:45px;
border-radius: 25px;
}
.footer_line{
width:100%;}
.p4_title_line{
width:100%;
max-width:30px;
}
.p5_bottom_img,.p5_bottom_img img{
width:100%;
z-index:2;
}
.top_img img, .top_img{
width:100%;
margin:0px;
}
.p2linedot{
width:100%;
max-width:35px;
border-radius: 25px;
margin-bottom:20px;
}
.p2_icon{
max-width:50px;
}
.p2_icon_block,.p3_tabs_sub_stack{
width:100%;
}
.tabs_tab a,.tabs_tab_hide_pc a{
border-radius: 10px;
}
.p4_tabs_tab a, .p2_stack_tabs a{
height:40px;
}
.p4_tabs_tab a sup{
font-size: 50%;
top: -12px;
left: 10px;
margin-left: -10px;
}
.p2_col_checkbox{
width:100%;}
.tabs_tab,.p3_tabs_tab,.p4_tabs_tab,.p5_stack{
width:100%;
}
.p2_wp_block{
width:100%;
}
.p2_list_1 ul.p2_tab_list_1,ul.p3_list,ul.p3_list_1_2,ul.p3_list_2,ul.p6_list ,ul.p2_tabs_list,ul.p2_list,ul.p4_list{
margin-left:0px;
}
.p2_list_1 ul.p2_tab_list_1{
margin:0px;
}
ul.p6_list,ul.p2_tabs_list{
margin-top:0px;
}
ul.p3_list,ul.p3_list_1_2,ul.p6_list,ul.p2_tabs_list, ul.p2_list, ul.p4_list{
margin-bottom:0px;
}
ul.p3_list_2{
width:100%;
margin:0px;
text-indent: -1.625em;
padding-left: 25px;
}
div.wp-block-group ul.p3_list_2 > li{
padding-left:0px;
margin-bottom: 0px;
}
ul.p2_list > li{
padding-left:0px;
}
.p2_list_1{
width:100%;
}
.p2_list_1 ul.p2_tab_list_1 li{
padding-left: 15px;
margin-bottom: 0px;
}
.p2_list_1 ul.p2_tab_list_1 li::before,[dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p2_tab_list_1 > li::before{
height: 0.4em;
width: 0.4em;
background-color:#912760;
}
.p2_list_1 ul.p2_tab_list_1 li ul li::before{
height: 0.4em;
width: 0.4em;
border: 1px solid;
background-color: transparent;
}
.p2_tab_icon{
max-width:190px;
}
.tabs_radio,.tabs_radio2{
background: #FFF3FB; border-radius: 25px;
}
.p2_5_sub_col{
width:100%;
}
.p2_5_sub_icon{
max-width:70px;}
.p2_5_icon{
min-width:150px;}
.p3_list li,.p3_list_2 li,.p6_list li,.p2_tabs_list li,.p2_list li,.p4_list li{
float: left;
}
div.wp-block-group ul.p3_list > li,div.wp-block-group ul.p3_list_1_2 > li{
background: #FFFFFF;
padding: 5px 10px;
border-radius: 25px;
min-width: 110px;
}
div.wp-block-group ul.p4_list > li{
background: #FFFFFF;
padding: 5px 10px;
border-radius: 25px;
min-width: 150px;
}
div.wp-block-group ul.p2_list > li{
background: #F6F7F7;
padding: 0 10px;
border-radius: 25px;
}
div.wp-block-group ul.p2_tabs_list > li,[dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p2_tabs_list > li{
background: white;
padding: 2px 6px;
border-radius: 12px;
color: #912760;
word-break: keep-all;
}
ul.p6_list > li{
margin-right: 10px;
}
ul.p2_tabs_list > li::before,[dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p2_tabs_list > li::before{
display:none;
}
div.wp-block-group ul.p3_list > li::before,div.wp-block-group ul.p6_list > li::before,div.wp-block-group ul.p3_list_1_2 > li::before,[dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p3_list > li::before,[dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p6_list > li::before,[dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p3_list_1_2 > li::before{
content: ‘\2713’;
display: inline-block;
position: relative;
top: 0px !important;
width: 18px;
height: 18px;
margin-right: 8px;
padding: 4px;
font-size: 12px;
font-weight: bold;
line-height: 11px;
border-radius: 50%;
text-align: center;
color: #FFF;
background: #912760;
}
ul.p4_list {
margin: auto;
text-align: center;
}
ul.p2_list strong{
min-width: 110px;
margin: auto;
text-align: center;
}
ul.p6_list strong{
margin: auto;
display: inline-block;
text-align: center;
}
div.wp-block-group ul.p2_list > li::before, [dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p2_list > li::before{
content: ‘\2713’;
display: inline-block;
position: relative;
top: 0px !important;
width: 18px;
height: 18px;
margin-right: 8px;
padding: 4px;
font-size: 12px;
font-weight: bold;
line-height: 11px;
border-radius: 50%;
text-align: center;
color: #FFF;
background: #912760;
text-indent: 0em;
}
div.wp-block-group ul.p3_list_2 > li::before, [dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p3_list_2 > li::before{
content: ‘\2713’;
display: inline-block;
position: relative;
top: 0px !important;
width: 18px;
height: 18px;
margin-right: 8px;
padding: 4px;
font-size: 12px;
font-weight: bold;
line-height: 11px;
border-radius: 50%;
text-align: center;
color: #FFF;
background: #912760;
text-indent: 0em;
}
div.wp-block-group ul.p4_list > li::before, [dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p4_list > li::before{
content: ‘\2713’;
display: inline-block;
position: relative;
top: 0px !important;
width: 25px;
height: 25px;
margin-right: 12px;
padding: 8px;
font-size: 15px;
font-weight: bold;
line-height: 10px;
border-radius: 50%;
text-align: center;
color: #FFF;
background: #912760;
text-indent: -2px;
}
.p4_stack{
width:100%;
}
.p4_arrow{
width:100%;
max-width:25px;
}
.p6_accordion section{
border-bottom:0px;
}
.p6_accordion section .mh-accordion-molecule-header{
background: #F0F0F0;
border-radius: 15px;
padding: 5px 20px;
margin-bottom: 10px;
}
.mh-accordion-molecule .mh-accordion-molecule-header__icon{
margin-right: 1.375rem;
max-height: 3.8125em;
max-width: 3.8125em;
}
#references{
word-break:break-all;
}
#references p{
text-align: justify;
margin-bottom: 15px;
}
#mh_header .mh-container{
min-height: 100px;
}
.mh-header–header-7 #mh_primary > ul > li > a{
padding-bottom: 0.15em;
padding-top: 0.15em;
max-height: 40px;
outline: none;
background: transparent;
}
li:has(.mh-megamenu–open){
color: #298C89;
border: 0.125rem solid;
border-radius: 25px;
padding: 0 0;
height: 40px;
}
#mh_primary ul.mh-submenu li:nth-child(1) a {
color: #005C55;
border: none;
padding:0px;
}
.mh-header–header-7 #mh_primary > ul > li > a{
padding-bottom: 0.15em;
padding-top: 0.15em;
max-height: 40px;
}
#mh_footer{
background:#FFF;}
div.mh-footer-note li:nth-child(1){
margin-right: auto;
}
#mh_footer > div.mh-footer-note > div > nav > ul.mh-footer-menu li:nth-child(2),ul.mh-footer-menu li:nth-child(7){
margin-left: auto;
}
.mh-footer-main-content{
max-width: 1200px;
margin: auto;
}
.mh-content__title{
display: none;
}
.mh-breadcrumb a,.mh-breadcrumb li{
color:#FFF;
}
.story_row_2{
width:100%;
}
.story_btn1{
width:225px;
}
.col2_3_col_p {
max-width: 180px;
}
.p4_img,.p7_img{
max-width:350px;
width:100%;
}
.mh-breadcrumb–align-full{
display:none;}
.wp-block-table{
width: 100%;
overflow: auto;
}
.col2_3,.col_block2 div,.col_block2 div div{
width:100%;
}
.wp-block-table table{
text-align: center;
}
.wp-block-table.p2_table td:nth-child(2),.wp-block-table.p2_table td:nth-child(3){
min-width: 280px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
width: 50%;
}
.wp-block-table.p2_table td:nth-child(1){
min-width: 150px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
}
.wp-block-table.p2_table_2 tr:nth-child(2) td:nth-child(1),.wp-block-table.p2_table_2 tr:nth-child(1) td:nth-child(1){
min-width: 130px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
}
.wp-block-table.p2_table_2 tr:nth-child(3) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(4) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(5) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(7) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(9) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(11) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(12) td:nth-child(1){
max-width: 50px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
color:#315996;
}
.wp-block-table.p2_table_2 tr:nth-child(1) td:nth-child(2){
min-width: 460px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
border-radius: 0px 15px 0 0;
}
.wp-block-table.p2_table_2 tr:nth-child(13) td:nth-child(4){
border-radius: 0px 0px 15px 0px;
}
.wp-block-table.p2_table_2 tr:nth-child(13) td:nth-child(1){
border-radius: 0px 0px 0px 15px;
}
.wp-block-table.p2_table_2 tr:nth-child(1) td:nth-child(2) ul{
margin:0px;
color:#000;
font-weight:500;
}
.wp-block-table.p2_table_2 tr:nth-child(2) td:nth-child(2),.wp-block-table.p2_table_2 tr:nth-child(2) td:nth-child(3){
min-width: 230px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
}
.wp-block-table.p2_table_2 tr:nth-child(3) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(5) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(9) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(13) td:nth-child(1){
min-width: 130px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
}
.wp-block-table.p2_table_2 tr:nth-child(3) td:nth-child(3),
.wp-block-table.p2_table_2 tr:nth-child(4) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(5) td:nth-child(3),
.wp-block-table.p2_table_2 tr:nth-child(6) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(7) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(8) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(9) td:nth-child(3),
.wp-block-table.p2_table_2 tr:nth-child(10) td:nth-child(1),
.wp-block-table.p2_table_2 tr:nth-child(11) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(12) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(13) td:nth-child(3){
min-width: 230px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
color:#000;
font-weight:500;
}
.wp-block-table.p2_table_2 tr:nth-child(3) td:nth-child(4),
.wp-block-table.p2_table_2 tr:nth-child(4) td:nth-child(3),
.wp-block-table.p2_table_2 tr:nth-child(4) td:nth-child(3),
.wp-block-table.p2_table_2 tr:nth-child(5) td:nth-child(4),
.wp-block-table.p2_table_2 tr:nth-child(6) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(7) td:nth-child(3),
.wp-block-table.p2_table_2 tr:nth-child(8) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(9) td:nth-child(4),
.wp-block-table.p2_table_2 tr:nth-child(10) td:nth-child(2),
.wp-block-table.p2_table_2 tr:nth-child(11) td:nth-child(3),
.wp-block-table.p2_table_2 tr:nth-child(12) td:nth-child(3),
.wp-block-table.p2_table_2 tr:nth-child(13) td:nth-child(4){
min-width: 230px;
border-right: 1px solid white;
border-bottom: 1px solid white;
padding:0px;
color:#000;
font-weight:500;
}
.wp-block-table thead,.wp-block-table thead th{
border-bottom: 0px solid;
}
.p2_table table tbody tr:nth-child(odd){
background-color:#F7F7F7;
}
.p2_table table tbody tr:nth-child(even){
background-color:#FFF3FB;
}
.p2_table_2 table tbody tr:nth-child(odd),.wp-block-table.p2_table_2 tr:nth-child(12) td:nth-child(1){
background-color:#FFF3FB;
}
.wp-block-table.p2_table_2 tr:nth-child(7) td:nth-child(1),.wp-block-table.p2_table_2 tr:nth-child(11) td:nth-child(1), .wp-block-table.p2_table_2 tr:nth-child(5) td:nth-child(1), .wp-block-table.p2_table_2 tr:nth-child(13) td:nth-child(1), .wp-block-table.p2_table_2 tr:nth-child(13) td:nth-child(2){
background-color:#F7F7F7;
}
.p2_table table thead th:nth-child(1){
background-color:#FFF3FB;
border-radius: 25px 25px 0 0;
padding-top: 10px;
}
.p2_table_2 table thead th:nth-child(1){
background-color:#FFF3FB;
border-radius: 10px 10px 0 0;
padding:5px 0px;
}
.p2_table_2 table thead th:nth-child(2){
width:0px;
}
.p2_table table thead th:nth-child(2),.p2_table table thead th:nth-child(3){
background-color:#F2F2F3;
border-radius: 25px 25px 0 0;
padding-top: 10px;
}
.p2_table table tbody td:nth-child(2),.p2_table table tbody td:nth-child(3){
color:#000;
font-weight: 500;
}
.p2_table table tbody td:nth-child(2) ul{
margin:0px;
display: inline-block;
width: 200px;
}
.p2_table table tbody td:nth-child(3) ul{
margin:0px;
display: inline-block;
width: 280px;
}
.p2_table ,.p2_table_2{
color:#912760;
font-weight: 700;
}
.p2_table table tbody tr:nth-child(4) td:nth-child(1){
border-radius: 0px 0px 0px 25px;
}
.p2_table table tbody tr:nth-child(4) td:nth-child(3){
border-radius: 0px 0px 25px 0px;
}
.p2_sub_col1 div.mh-columns-inner div.mh-column{
margin:0px;
}
.p4_list{
max-width:600px;
}
.support_btn1{
width: 240px;
}
.QA_btn1{
width:250px;
}
figure.lightning{
width:200px;
margin:auto;
}
div.wp-block-group ul.p4_tab_list_1 li::before, [dir=ltr] ul.mh-v2-clist.mh-v2-clist–dot.p4_tab_list_1 > li::before{
background-color:#912760;
}
ul.p4_tab_list_1 li{
margin: 0;
}
ul.p4_tab_list_1 {
margin: 0px;
padding: 0px;
}
.wordkeep{
word-break: keep-all;
}
#mconnect-theme-banner-container-4373 > div > div > div > div > div.banner__content.sub__entry__content > div > a,#mh_back_to_top_link > a,.cta_btn{
background-color:#912760;
border: 1px #FFF solid;
}
.mh-tabs–primary .mh-tabs-nav .mh-tabs-control .mh-tabs-control-next,.mh-tabs–primary .mh-tabs-nav .mh-tabs-control .mh-tabs-control-prev{
padding: 0px 8px;
height: 40px;
}
sup{
white-space: pre;
}
.mh-nav-side-accordion ul li{
margin: 20px 0;
}
.w100{
width:100%;
}
.m0{
margin:0;
}
.mh-nav–primary li:hover{
color: #298C89;
border-bottom: 0.125rem solid;
padding: 0 0;
height: 40px;
}
.mh-nav–primary .mh-submenu li:hover{
color: #298C89;
border: none;
padding: 0 0;
height: 40px;
}
.footer_code::before {
content: “HK-KEY-00957/Jun 2025”;
color:#000;
}